TERT (Ref/SLC12A7/228T/C242T-C243T/C250T/TSN) Crystal Digital PCR® Assay

Oncology

Assay-specific Crystal Flex Probes and primers for the detection of TERT mutations and its Positive Control.

For Research Use Only. Not for use in diagnostic procedures.

Wet-lab tested

Compatibility

Channels

Blue
Teal
Green
Yellow
Red
Infra-Red

Required Reagents

Gene

Product Details

TERT (Ref/SLC12A7/228T/C242T-C243T/C250T/TSN) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 3 mutations in the TERT gene using the Ruby Chip. Three references are detected and used to quantify TERT gene amplification: a reference on the TERT gene, a reference on a gene located on the same chromosome as TERT (SLC12A7) and a reference on a different chromosome (TSN).
This assay is available in 200 and 1000 reaction formats.
TERT plays a critical role in cellular mechanisms linked to cancer progression, notably in maintaining telomere length and promoting immortalization.

Base changes:
TERT C228T: c.-124C > T
TERT C242T-C243T: c.-138/c.-139 C > T
TERT C250T: c.-146C > T

Features & Benefits

Ready-to-use assay reagents to detect multiple targets in a single reaction
Crystal Flex Probe detection chemistry for flexible assay configuration
Same set of Crystal Universal Reporters to detect any target in different assays

Targets

TERT Ref / C228T / C242T-C243T / C250T

SLC12A7

TSN

Assays & kits

Ready-to-use assays & kits

Explore our catalogue of assays and kits and take a leap into the world of multiplexing. Crystal Digital PCR® assays and kits allow for the detection of multiple targets of interests within one single Ruby Chip chamber.

Custom assay design services

Rapid high-plex assay customization

Stilla offers the fastest assay design service in the market for multiplexed digital PCR assays. Stilla exploits its proprietary Crystal Flex Probe PCR chemistry to offer customized assays in record time, at competitive prices.