MLH1 Methylation Crystal Digital PCR® Assay

Oncology

Assay-specific Crystal Flex Probes and primers for the detection of MLH1 Methylation and its Positive Control.

For Research Use Only. Not for use in diagnostic procedures.

Wet-lab tested
Product Details

The MLH1 Methylation Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify methylation in the promoter of MLH1 gene using the Ruby Chip. MLH1 is involved in DNA mismatch repair and promoter hypermethylation is the most common reason of gene inactivation. This is an important cause for genomic instability and cell proliferation in several cancers, notably in colorectal and endometrial cancers.

Features & Benefits

Ready-to-use assay reagents to detect multiple targets in a single reaction

Crystal Flex Probe detection chemistry for flexible assay configuration

Same set of Crystal Universal Reporters to detect any target in different assays

Targets

MLH1 promoter methylation

Assays & kits

Ready-to-use assays & kits

Explore our catalogue of assays and kits and take a leap into the world of multiplexing. Crystal Digital PCR® assays and kits allow for the detection of multiple targets of interests within one single Ruby Chip chamber.

Custom assay design services

Rapid high-plex assay customization

Stilla offers the fastest assay design service in the market for multiplexed digital PCR assays. Stilla exploits its proprietary Crystal Flex Probe PCR chemistry to offer customized assays in record time, at competitive prices.