MGMT Methylation Crystal Digital PCR® Assay
Assay-specific Crystal Flex Probes and primers for the detection of MGMT promoter methylation and its Positive Control.
For Research Use Only. Not for use in diagnostic procedures.
Compatibility
Channels
Required Reagents
The MGMT Methylation Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify methylation in the promoters of the MGMT gene using the Ruby Chip. MGMT plays critical roles in DNA repair mechanisms: MGMT is involved in the direct reversal of DNA alkylation damage. Promoter hypermethylation is the most common mechanism of gene silencing for both, leading to loss of function. This epigenetic inactivation contributes significantly to genomic instability and uncontrolled cell proliferation in a variety of cancers.
This assay is available in 200 and 1000 reaction formats.
Ready-to-use assay reagents to detect multiple targets in a single reaction
Crystal Flex Probe detection chemistry for flexible assay configuration
Same set of Crystal Universal Reporters to detect any target in different assays
MGMT promoter methylation
Ready-to-use assays & kits
Explore our catalogue of assays and kits and take a leap into the world of multiplexing. Crystal Digital PCR® assays and kits allow for the detection of multiple targets of interests within one single Ruby Chip chamber.
Rapid high-plex assay customization
Stilla offers the fastest assay design service in the market for multiplexed digital PCR assays. Stilla exploits its proprietary Crystal Flex Probe PCR chemistry to offer customized assays in record time, at competitive prices.
