IDH1 (R132, R132C, R132H) Crystal Digital PCR® Assay

Oncology

Assay-specific Crystal Flex Probes and primers for the detection of IDH1 mutations and its Positive Control.

For Research Use Only. Not for use in diagnostic procedures.

Wet-lab tested
Product Details

The IDH1 (R132, R132H, R132C) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 2 mutations in the Isocitrate Dehydrogenase 1 (IDH1) gene using the Ruby Chip. IDH1 encodes an enzyme that catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate (α-KG). It is involved in energy metabolism (Krebs cycle). Mutations in IDH1 – particularly R132H – are found in several cancers, most notably in Gliomas and Acute myeloid leukemia (AML).

Features & Benefits

Ready-to-use assay reagents to detect multiple targets in a single reaction

Crystal Flex Probe detection chemistry for flexible assay configuration

Same set of Crystal Universal Reporters to detect any target in different assays

Targets

IDH1 R132, R132C, R132H

Assays & kits

Ready-to-use assays & kits

Explore our catalogue of assays and kits and take a leap into the world of multiplexing. Crystal Digital PCR® assays and kits allow for the detection of multiple targets of interests within one single Ruby Chip chamber.

Custom assay design services

Rapid high-plex assay customization

Stilla offers the fastest assay design service in the market for multiplexed digital PCR assays. Stilla exploits its proprietary Crystal Flex Probe PCR chemistry to offer customized assays in record time, at competitive prices.