EGFR CNV (vIII, KDD) Crystal Digital PCR® Assay

Oncology

Assay-specific Crystal Flex Probes and primers for the detection of EGFR vIII and EGFR KDD and its Positive Control.

For Research Use Only. Not for use in diagnostic procedures.

Wet-lab tested

Compatibility

Channels

Blue
Red
Yellow
Infra-Red

Required Reagents

Gene

Product Details

The EGFR CNV (vIII, KDD) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify EGFR duplication, EGFR variant III (deletion exons2-7) and EGFR Kinase Domain Duplication (exons 18-25 duplication) using the Ruby Chip. The copy number variation (CNV, i.e. duplication or deletion of gene or gene fragment) is given by the ratio of the estimated concentration of the target gene to the estimated concentration of the reference gene.

EGFR encodes for the epidermal growth factor receptor, a protein that plays a crucial role in cell growth, proliferation, and differentiation.

This assay is available in 200 and 1000 reaction formats.

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Features & Benefits

Ready-to-use assay reagents to detect multiple targets in a single reaction

Crystal Flex Probe detection chemistry for flexible assay configuration

Same set of Crystal Universal Reporters to detect any target in different assays

Targets

HMBS ref, EGFR ref, EGFR vIII, EGFR KDD

Assays & kits

Ready-to-use assays & kits

Explore our catalogue of assays and kits and take a leap into the world of multiplexing. Crystal Digital PCR® assays and kits allow for the detection of multiple targets of interests within one single Ruby Chip chamber.

Custom assay design services

Rapid high-plex assay customization

Stilla offers the fastest assay design service in the market for multiplexed digital PCR assays. Stilla exploits its proprietary Crystal Flex Probe PCR chemistry to offer customized assays in record time, at competitive prices.