Trade Up to Nio™ Digital PCR

Unlock fast, accurate, and high-multiplexing for your dPCR workflow.

Boost Your Lab’s Efficiency.

Why Upgrade to Nio™?

Our systems, available in three configurations to perfectly fit your needs (Nio™E, Nio™, and Nio™+), are accurate, convenient, and comprehensive, guaranteeing a streamlined workflow and best-in-class capabilities.
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Higher throughput: Nio™+ handles up to 24 PCR programs per run and processes up to 768 samples daily, maximizing productivity in your laboratory.
Higher-multiplexing: Nio™ Digital PCR is the only 7-color instrument on the market. Combined with our Crystal Digital PCR® technology, you can achieve well over 21 targets in a single chamber.

fits seamlessly into your lab & accelerates your research

Embrace simplicity

With the smallest all-in-one dPCR system and a 21.5-inch touch display, manage your workflow effortlessly—from the interface or remotely.
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We handle the removal of your old dPCR system, making the upgrade hassle-free.‍

Just Press Play

Add your samples, insert the Chip Plates, and press play. No more oils, plate transfers, or multiple formats—just a simple process.

Optimal Dimensions

built to fit into any environment without the clutter.
W 560mm | 22"
H 521mm | 20.5"
D 671,5mm | 26.4"

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One unique consumable

Ruby Chips

Ruby enables the analysis of up to 384 samples per run when used with Nio™+, offers seamless integration with automated liquid handling systems, and is compatible with multichannel micropipette usage.
With a capacity of 16 samples per chip, 5 µL input volume per chamber, and up to 15,000 droplets per sample, Ruby delivers precise results with a dynamic range of ~4.7 log.

Ready to use

Pre-filled with oil and ready to go—no sealing required.

Adaptable depth

You can pull together multiple wells and increase the partition.

WATCH on-demand webinarsUpgrade now

Stilla®’s Crystal Flex Probe technology

Extensive Assays Catalogue

Nio™ Digital PCR and Ruby Chips don't come alone. our Crystal Digital PCR® assays and kits allow for the detection of multiple targets of interest within one single Ruby Chip chamber.

Do you have a research project that requires specific biomarkers? The combination of our Crystal Universal Reporters and our target-specific Crystal Flex Probes allows for easy, quick, and affordable customization.

Learn MoreDownload our brochure
Don’t let outdated systems hold you back.

Adopt Nio™ Digital PCR!

This Promotion is valid until June 30, 2025, and is subject to the Terms and Conditions of the Promotion. The Promotion applies to the full list price of a Nio™ Digital PCR system and does not include any required reagents or consumables. The Promotion is void where prohibited and cannot be combined with other offers or promotions. It is valid only in the United States and Canada. Freight and delivery costs are not included. This Promotion is time-limited and subject to specific restrictions outlined herein. The customer is responsible for ensuring that participation in this Promotion complies with their organization's internal policies and all applicable laws and regulations.
Discover Nio™ Digital PCR

Request a quote below and a digital PCR specialist will be in touch.