Upgrade to Digital PCR that works with your lab. Not against it.
With Nio™ Digital PCR, you can detect up to 21 targets in one sample and run up to 768 samples per day. On a single instrument.
Most digital PCR systems require a lot of manual handling and have limited targeting capabilities.
High manual effort.
Multiple sample-loading steps and plate transfers between instruments requires additional hands-on time, leading to higher error margins.
Limited targeting capabilities.
Targeting more sequences in a single reaction requires complex assays and is limited by your hardware.
Complex, clunky software.
Software that feels like out of the 90s and seeing your raw data is harder than solving a Rubik's Cube
Meet Nio™: the simplest, most powerful digital PCR workflow.
Consistent and precise absolute quantification, run after run.
Intuitive software
Enjoy modern, intuitive software that visualizes data across dimensions and simplifies every step from setup to analysis. Control-freak? You can even see the droplets if you'd like.
Simplified handling
SBS-compatible chip plates, allowing continuous loading and automated liquid handling. Saving hours and reducing repetitive tasks.
21 Target Detection, Unmatched Precision
The only 7-color digital PCR system on the market, supporting assays with up to 21 unique targets per reaction. Effortlessly manage complex experiments.
Ready-to-run assays
Use your existing assays or upgrade your targeting capabilities with our high-multiplex assay catalog.
Ready to upgrade your digital PCR workflow?
Upgrade your system and unlock up to 25% off on a new Nio™ Digital PCR.
Intuitive Software.
Limitless Control.
Designed for scientists, by scientists, NioTM software offers seamless data visualization, analysis, and flexibility that adapts to your needs — no steep learning curve, just intuitive control.
AI-powered quality control
Nio™’s automated droplet counting ensures precise control over droplet size, delivering precise, accurate results, run after run.
Simple experiment configuration
Configure multiple experiments with ease, right at your desk or on the Nio™ Digital PCR itself. No confusing menus or clunky interfaces; simply select, load, and go.
Every detail, fully revealed.
Nio™ software brings your data to life across multiple dimensions. Automated or manual thresholding lets you dive deep with precision, ensuring every result is clear and easy to interpret.
21 CFR pt. 11 compliant
For labs needing strict compliance, Nio™’s regulatory software supports user management, audit trails, electronic signatures, and PDF reporting. Your data is safe, secure, and audit-ready.
One chip.
No compromises.
Prefilled with oil, compatible with multi-channel pipettes and ready to go. With just 5 µL input volume and 17,000 droplets per chamber, Ruby Chip achieves unmatched sensitivity and precision.
Max results with minimal sample
Designed for efficiency, Ruby needs only 5 µL of sample. For even higher sensitivity, just split your sample across multiple chambers.
Just add sample
Pipet, set, run. Ruby’s pre-filled oil system eliminates liquids in the instrument, meaning no calibrations, no cleanup, and no hassles.
One chip, unlimited applications
Whether your priority is high sensitivity with limited sample or peak precision, Ruby adapts to your needs. Use a single chamber for minimal sample, or pool chambers for maximum precision.
Effortless sample tracking
No more mixing up of your precious samples. Write your loaded map directly on the chip and see which chambers you've loaded.
Ready to upgrade your digital PCR workflow?
Upgrade your system and unlock up to 25% off on a new Nio™ Digital PCR.
Quantify 4x more targets in a single assay using color combination
Nio™ Digital PCR is the only 7-color instrument on the market. While our system provides easy access to 7 target capabilities, you can leverage our Crystal Flex Probes assay technology and detect up to 21 targets seamlessly - simply assign 2 distinct channels to each target.
Our systems, available in three configurations to fit your needs (Nio™ E, Nio™, and Nio™+), are designed to be precise, user-friendly, and comprehensive, guaranteeing seamless workflow and exceptional performance.
21 targets per reaction
Detection and quantification of up to 21 targets in a single reaction, unmatched by any other provider.
Ready-to-run assays
Stilla® offers a comprehensive portfolio of high-multiplex digital PCR assays for numerous applications.
“The main difference that we experience from the workflow with droplet digital PCR® to the Nio™ workflow is the transferring of plates from one machine to the other. If you have four machines instead of one, of course you have to move from one machine to the other.”
Co-Coordinator, Digital PCR Consortium
"Using the Nio™ we experienced peace of mind. Thanks to the continuous loading you never need to worry about the availability of the machine."
"The Nio™ workflow is a breeze. The software is very intuitive. It’s a machine that works together with you and offers the flexibility for multiple users to run experiments on the same day."
Co-Coordinator, Digital PCR Consortium
"It's a compact machine, fully integrated with an easy-to-use interface. For me, it's the best."
Upgrade your digital PCR workflow.
Upgrade your system and unlock up to 25% off on a new Nio™ Digital PCR. Use the form below to request a quote!
Terms and Conditions:
This Promotion is valid until February 15, 2025, and is subject to the Terms and Conditions of the Promotion. The Promotion applies to the full list price of a Nio™ Digital PCR system and does not include any required reagents or consumables. The Promotion is void where prohibited and cannot be combined with other offers or promotions. It is valid only in the United States and Canada. Freight and delivery costs are not included. This Promotion is time-limited and subject to specific restrictions outlined herein. The customer is responsible for ensuring that participation in this Promotion complies with their organization's internal policies and all applicable laws and regulations.